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Male factor infertility is more common than you might think, contributing to around one-third of infertility cases. Most cases are related to the quality or quantity of sperm in ejaculated semen. With the right diagnosis and treatment, many cases can be managed effectively. Our specialists will work with you to identify the cause and recommend the most appropriate next steps for your situation.
Male factor infertility can stem from factors affecting the production, quality or delivery of sperm. These are some of the most common types of male infertility:
Hormonal imbalances, genetic conditions, blockages in the reproductive tract, and testicular injury or infection can also contribute to infertility in men. In some cases, lifestyle and environmental factors play a role too.
Male infertility doesn’t close the door to conception. Our fertility specialists can help identify the cause and guide you toward the most effective treatment.
ICSI (intracytoplasmic sperm injection) is an advanced fertilisation technique in which a single sperm is injected directly into an egg. Unlike conventional IVF, which requires several million sperm, ICSI can be effective with just one, making it an important option for those facing male factor infertility.
Sperm freezing, or cryopreservation, provides a safe and reliable way to preserve your fertility - giving you flexibility, reassurance and control over your future. Whether you’re doing it for medical reasons or personal choice, it’s a straightforward and effective way to plan with confidence.
Surgical sperm retrieval is a procedure used to collect sperm directly from the epididymis or testicle. It may be recommended when sperm is absent - due to a blockage, vasectomy or a problem with sperm production - and is typically used alongside ICSI to give you the best chance of fertilisation.
Male infertility doesn’t close the door to conception. Our fertility specialists can help identify the cause and guide you toward the most effective treatment.
The first and most essential male test for infertility. It assesses sperm count, movement, shape, and overall quality. A second sample may be recommended for accuracy.
Blood tests measure hormones such as FSH, LH, testosterone and prolactin to identify whether sperm production issues are linked to hormonal imbalance.
Used when sperm counts are very low or absent, helping diagnose chromosomal conditions or Y-chromosome microdeletions.
For men with azoospermia, a biopsy helps determine whether sperm are being produced inside the testes and, if found, whether they can be used for treatment.
Antioxidants (including vitamins C and E), zinc, selenium, folic acid, omega-3 fatty acids and CoQ10 may support sperm health. Always speak to a fertility specialist before starting supplements to ensure they’re appropriate for your situation.
The most effective treatments for male infertility are primarily Intracytoplasmic Sperm Injection (ICSI) and, when needed, surgical sperm retrieval. Medical treatments that address underlying conditions – such as hormone imbalances, infections, or anatomical blockages – can also improve fertility. Many patients benefit from a personalised combination of lifestyle changes, medical management, and assisted reproductive techniques. Book a fertility health assessment to discuss the right pathway for you.
The most common sign of male infertility is difficulty conceiving. Other symptoms may include changes in sexual function, testicular swelling or discomfort, a lump in the scrotum, or signs of hormonal imbalance such as reduced body or facial hair. Persistent fatigue or other ongoing health concerns can also indicate an underlying issue. It’s best to get checked out by a doctor if you experience any of these symptoms.
The main causes of male factor infertility include issues with sperm production (such as low or no sperm count), blockages in the reproductive tract, hormonal imbalances, genetic conditions, lifestyle factors, infections, testicular injuries, ejaculation disorders, and varicocele.
Stay informed about the latest seminars, webinars and workshops on fertility and Male Factor Infertility.
Explore expert insights, personal stories and the latest research to guide you through every step of your Male Factor Infertility journey.
David Williams OBE, Chair of JD Healthcare Group, has retired after more than 20 years of transformative leadership, guiding the growth of London Women’s Clinic from a single Harley Street clinic to over 20 UK locations. He leaves a lasting legacy of clinical excellence, mentorship, and dedication to both colleagues and patients.
On Saturday 18th April, 600 people walked through the doors of the De Vere Grand Connaught Rooms in London for the fourth Familymakers Show — and the energy in the room felt like something that has been a long time in the making. Because in many ways, it has.
"If she hadn't made that phone call, I would never have known that embryo had a chance..." At 46, having already been through three IVF cycles and preparing to begin donor egg treatment, Ella had almost given up on the idea of becoming a mother using her own eggs. Then an embryologist at London Women's Clinic made a call that changed everything. This is the story of one frozen embryo, a DNA swab sent from overseas, and the four-year-old girl who is now the light of her mother's life — and why advances in genetic embryo testing are making the seemingly impossible possible.
Michelle was 39 when she walked into a London Women's Clinic open day, already certain of one thing: she didn't want to waste time. What followed was two IVF cycles, a devastating first round where no embryos were chromosomally normal, a mosaic result, and an embryo that came back from retesting as something extraordinary — euploid, chromosomally normal, and ready to become her daughter.
If you’re concerned about your sperm health or want to know more about male infertility treatment, our team is here to help. Book a fertility health assessment and speak to a specialist today.
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